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Beximco Pharmaceuticals Ltd.
Kovicin 200 mg Tablet
Generic: Hydroxychloroquine Sulphate
৳১২/ PCS
ইউনিট টাইপ নির্বাচন করুন
১
সারা বাংলাদেশে ৩-৫ দিনের মধ্যে ডেলিভারি
ভুল বা ক্ষতিগ্রস্ত পণ্যে ২৪ ঘণ্টার মধ্যে সহজ রিটার্ন
১০০% আসল পণ্য, মান যাচাইকৃত ও নিরাপদ প্যাকেজিং
পণ্যের বিবরণ
Indications
Kovicin is indicated in- Acute and chronic rheumatoid arthritis Systemic Lupus Erythematosus (SLE) Malaria
Pharmacology
Hydroxychloroquine Sulphate synthetically produced version of quinine. It acts as an immunosuppressant by inhibiting production of rheumatoid and acute phase reactants. It also accumulates in white blood cells, stabilizing lysosomal membranes and inhibiting the activity of many enzymes, including collagenase and the proteases that cause cartilage breakdown. It also acts by disrupting cell walls of infected red blood cells and kills the developing parasites.
Dosage & Administration
Hydroxychloroquine Sulphate tablets are for oral administration and are taken with food to avoid stomach upset.Acute and chronic rheumatoid arthritis: 400 to 600 mg daily. When good response is obtained (usually 4 to 8 weeks), dose can be reduced to 50%.Systemic Lupus Erythematosus (SLE): 400 mg once or twice daily for several weeks or months depending on response of the patients. Maintenance dose is 200 to 400 mg daily.Malaria: In adults, an initial dose of 800 mg followed by 400 mg in 6-8 hours and 400 mg on each of two consecutive days. For children a total dose representing 25 mg/kg is administered in 3 days as follows. First dose: 10 mg base/kg (but not exceeding a single dose of 620 mg base).Second dose: 5 mg base/kg (but not exceeding a single dose of 310 mg base) 6 hours after first dose.Third dose: 5 mg base/kg 18 hours after second dose.Fourth dose: 5 mg base/kg 24 hours after third dose.
Interaction
Drug interaction with medication: Kovicin sulfate may interact with digoxin insulin or antidiabetic drugs, mefloquine, antiepileptics, methotrexate and cyclosporine.
Contraindications
Hydroxychloroquine sulfate is contraindicated in patients with known hypersensitivity to hydroxychloroquine or any other components of this product.
Side Effects
Generally Kovicin is well tolerated. However, few side effects like nausea, vomiting, stomach upset, loss of appetite, diarrhea, tiredness, weakness or headache and visual problem may occur the first several days.
Pregnancy & Lactation
During pregnancy, this drug should be used only if clearly needed. Since small amounts of this medication are found in breast milk consult your doctor before medication.
Precautions & Warnings
Children are especially sensitive to the 4-aminoquinoline compounds. Patients should be strongly warned to keep these drugs out of the reach of children. Opthalmologic examination requires in every 12 months.
Use in Special Populations
Use in children and adolescents: The use in children and adolescents is given in dose and administration section.
Overdose Effects
Symptoms of overdose consist of headache, drowsiness, visual disturbances, cardiovascular collapse and convulsions followed by sudden and early respiratory and cardiac arrest. Gastric lavage until the stomach is completely emptied.
Therapeutic Class
Anti-malarial drugs, Disease-modifying antirheumatic drugs (DMARDs), Drugs used for Rheumatoid Arthritis
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
